Septoplasty: Proven Effective for Treating a Deviated Nasal Septum

The NAIROS study, a major UK clinical trial published in The BMJ, has shown that septoplasty (surgery to straighten a deviated nasal septum) is a highly effective treatment for adults suffering from persistent nasal blockage.

In this large study involving 378 patients across 17 NHS hospitals, researchers compared the results of septoplasty with medical treatment using nasal steroid and saline sprays. After six months, patients who underwent septoplasty reported much greater improvement in breathing, sinus symptoms, and quality of life compared with those who used sprays alone.

Results of trial into Septoplasty for deviated septum

On average, symptom scores in the surgical group improved twice as much as those managed with medication. Patients also experienced better nasal airflow and overall comfort.

While minor side effects such as temporary bleeding or infection occurred in a small number of patients, the study confirmed that septoplasty is safe and provides long-lasting relief for people whose nasal obstruction is caused by a deviated septum.

If you continue to experience nasal blockage, congestion, or difficulty breathing through your nose despite using nasal sprays, septoplasty may offer a permanent solution. Our ENT specialists can assess your nasal airflow and discuss whether this proven surgical treatment is right for you.

Endoscopic Sinus Surgery: Proven Effective Treatment for Chronic Sinus Problems

The MACRO study, a large UK clinical trial published in the Lancet, has provided strong evidence that endoscopic sinus surgery (ESS) is an effective treatment for adults with chronic rhinosinusitis (CRS) — persistent inflammation of the sinuses that causes nasal blockage, facial pressure, and reduced quality of life.

The trial compared surgery with medical treatments, including three months of antibiotic therapy and standard intranasal medications (nasal sprays and rinses). Over 500 patients were involved across 20 hospitals.

Results of the Endoscopic Sinus Surgery trial

Results showed that patients who underwent endoscopic sinus surgery experienced significantly greater improvements in sinus symptoms and quality of life than those who received only medication. In contrast, long-term antibiotic treatment did not offer meaningful benefits.

These findings confirm that endoscopic sinus surgery is a safe and effective option for patients whose symptoms persist despite medical therapy. For many people living with chronic sinus problems, surgery can restore nasal function, improve breathing, reduce infections, and enhance overall wellbeing.

Arrange a sinus surgery consultation

If you have ongoing sinus symptoms that have not improved with medication, our ENT specialists can discuss whether endoscopic sinus surgery is suitable for you.

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CLINICS

  • BMI The London Independent Hospital
  • London Bridge Hospital Part of HCA Healthcare UK
  • Hospital of St John & St Elizabeth